Paul Reiser’s character is an affluent New York psychiatrist who has the perfect life until one day he is diagnosed with a termination illness, and his only chance of survival is a bone marrow transplant from a member of his immediate family, preferably a sibling. When he informs his mother, she confesses that he was adopted as a baby while she and her husband lived in England.
He travels to England to find his birthmother and has no problem finding her. To his surprise, he learns from her that he has two brothers, and he quickly becomes genuinely fond of his birth mother and his brothers. He seeks to find out if he and his brothers are compatible for a bone marrow transplant, without telling them the true reason for his suggestion that they both a blood test.
He is surprised about his honest feelings for his newly discovered family because his background and life style are so totally different, but they become an important part of his life.